Nutrition Guide

John Bosley Ziegler, John Ziegler, Montana Jack, (circa 1920 - 1983) was an American physician who originally developed the anabolic steroid Methandrostenolone (Dianabol, DBOL) which was released in the USA in 1958 by Ciba[1][2]. He pioneered its athletic use as an aid to muscle growth by bodybuilders, administering it to U.S. weightlifting champion Bill March of the York Barbell club in 1959 when he was the physician to the U.S. Weightlifting team[3]. It was banned by the Food and Drug Administration (FDA) under the Controlled Substances Act. In later life he was outspoken against its use in sport, saying “It is bad enough to have to deal with drug addicts, but now healthy athletes are putting themselves in the same category. It’s a disgrace. Who plays sports for fun anymore?”[4]. Ziegler suffered from heart disease, which he partially ascribed to his experimentation with steroids, and he died from heart failure in 1983.

No trenbolone compounds have been approved by the FDA for human use,[1] due to a lack of clinical applications and some potential negative side-effects.[2] It is classified as a Schedule III drug under the Controlled Substances Act. However, bodybuilders and athletes have been known to use the drug illicitly in order to increase body mass more effectively than by weight training alone. A normal bodybuilding dosage can range from 200 mg/week up to 1400 mg/week. Due to the relatively short metabolic half-life of trenbolone acetate, dosages should commonly be split into injections at least once every two days. Trenbolone enanthate can be injected once a week.

Trenbolone acetate is often referred to as “Fina” by users, because injectible trenbolone acetate is often prepared from Finaplix H pellets, an ear-implant used by cattle ranchers to maintain the weight of cattle during shipping to slaughter.

Trenbolone compounds have a binding affinity for the androgen receptor three times as high as that of testosterone.[3] Once metabolised, the drugs have the effect of increasing nitrogen uptake by muscles, leading to an increase in the rate of protein synthesis. It also has the secondary effects of stimulating appetite, reducing the amount of fat being deposited in the body, and decreasing the rate of catabolism. Trenbolone has proven popular with anabolic steroid users as it is not metabolised by aromatase or 5?-reductase into estrogenic compounds such as estradiol, or into DHT. This means that it also does not cause any water retention normally associated with highly androgenic steroidal compounds like testosterone or methandrostenolone. It is also loved by many for the dramatic strength increases commonly experienced with it.

Short-term side effects include insomnia, high blood pressure, increased aggression, night sweats, and increased libido. However, since women will suffer virilization effects even at small doses, this drug should not be taken by a female. Urban wisdom/myth in bodybuilding culture, states that the use of the drug over extended periods of time can lead to kidney damage. The kidney toxicity has not yet been proven, and scientific evidence supporting the idea is suspiciously absent from the bodybuilding community that perpetuates this idea. The origin of this myth most likely has to do with the rust colored oxidized metabolites of trenbolone which are excreted in urine and often mistaken for blood. After Schänzer (Clin Chem 1996; 42(7): 1001-1020, Metabolism of anabolic androgenic steroids) trenbolone and 17epi-trenbolone are both excreted (in urine) as conjugates that can be hydrolyzed with beta-glucuronidase. This implies that trenbolone leaves the body as beta-glucuronides or sulfates, which means mostly non metabolized.

Trenbolone is a steroid used by veterinarians on livestock to increase muscle growth and appetite. To increase its effective half-life, trenbolone is not used in an unrefined form, but is rather administered as trenbolone acetate (Finaplix Gold from Valopharm USA, TREMBLONA QV75 from Quality Vet, Mexico), Trenbolone enanthate or Trenbolone cyclohexylmethylcarbonate (Parabolan from Laboratoires NEGMA until 1997). Plasma lipases then remove the ester in the bloodstream leaving free trenbolone.

For a time, THG was considered the drug of choice for safe and “invisible” world record breaking in athletics, being used by several high profile gold medal winners such as the sprinter Marion Jones, who resigned from her athletic career in 2007 after admitting to using THG prior to the 2000 Sydney Olympics, where she had won three gold medals.[8] It has also been used by banned British athlete Dwain Chambers.

THG was developed by Patrick Arnold for the Bay Area Laboratory Co-operative (BALCO), an American nutritional supplement company.[9] The company manufactured the drug through palladium-charcoal catalyzed hydrogenation from gestrinone, a substance used in gynecology for treatment of endometriosis.[citation needed]

Side effects from prolonged use are likely to include infertility in both men and women, as well as other steroid side effects such as acne and hirsutism.[6] Unlike most other anabolic steroids, THG also binds with high affinity to the glucocorticoid receptor, and while this effect may cause additional weight loss, it is also likely to cause extra side effects such as immunosuppression that are not seen with most other steroids.[7]

Structure-activity relationship studies report that the potency of the drug is outstanding, surpassing, on a milligram per milligram basis, every known synthesized or commercial available anabolic steroid at the time of its development. It is a highly potent agonist for the androgen and progesterone receptors,[4] around 10 times more potent than the comparison drugs nandrolone or trenbolone, but with no estrogenic activity. It has been found to bind to the androgen receptor with similar affinity to dihydrotestosterone and produces growth of muscle tissue.[5

Tetrahydrogestrinone (often referred to as THG or The Clear) is an anabolic steroid. It has affinity to the androgen receptor and the progesterone receptor, but not to the estrogen receptor.[1] The drug has been considered a designer drug, closely related to the banned anabolic steroids gestrinone and trenbolone,[2] and was banned by the Food and Drug Administration (FDA) at the end of 2003

Sustamed 250 is a genericized trademark for an oil-based injectable blend of four esterized testosterone compounds.
30mg Testosterone Propionate
60mg Testosterone Phenylpropionate
60mg Testosterone Isocaproate
100mg Testosterone Decanoate

Sustamed is produced by Balkan Pharmaceuticals in Republic of Moldova.

For therapeutic information and other details, refer to the article on Testosterone.

Strombafort is a genericized trademark for Stanozolol compound, being a synthetic anabolic steroid derived from testosterone. Stanozolol was developed by Winthrop Laboratories and is produced for human use by Zambon in Spain and Balkan Pharmaceuticals in Republic of Moldova.

For therapeutic information and other details, refer to the article on Stanozolol.

A steroid stack is a slang term used to describe the combination of two or more anabolic steroids used ideally in synergy for a period commonly ranging from 2 to 10 weeks or even more (see steroid cycle). At the end of a steroid cycle, advanced bodybuilders often take mild dosages of steroids less likely to interfere with the body’s HPTA. Deca or Primobolan are common examples. They are used for a period of 6-12 weeks to “bridge” between cycles and help maintain the gains they made while “on”.